What Are The Differences Between R-22 & R-410A?

Hello folks and welcome! Today on RerigerantHQ we will be comparing the main differences between the HCFC R-22 refrigerant to the newer HFC R-410A refrigerant. R-410A has been around for nearly ten years now but there are still so many questions asked about it. How is it different from R-22? What do I need to know? Can I use the same tools? Can I retrofit a R-22 over to a R-410A?

Rather than going over every single question that could be asked I am going to give a simple highlighted article  in an attempt to answer some of the more popular questions. If I missed something let me know.

The Differences

  • Unlike R-22 the new R-410A is a blended refrigerant mixed up of R-32 and R-125. In some instances blended refrigerants act differently then single refrigerants. We will get into that further on down this list.
  • R-410A is actually more efficient at absorbing heat then R-22. What that means is that your air conditioner won’t work as hard and your home will stay cooler all the while saving on your power bills.
  • 410A operates at a much higher pressure than R-22, between fifty to sixty percent higher. To accommodate this increased pressure the compressors and other components are built to withstand the greater stress. Some people describe these components as having a ‘thicker wall.’ If you were to use an R-22 compressor on a 410A application your compressor would blow it’s head! The extra toughness of these components come with the extra bonus of ensuring a longer life of your air conditioner.
  • Because of the higher pressure of Puron you will need to have special tools in order to service the unit. I will go into this further in the tools section but I wanted to point it out now. R-22 tools will NOT work on 410A!
  • Instead of the mineral oil lubricant you would use for R-22 you will be using a synthetic oil called Polyol Ester Oil, or POE. This oil is actually more soluble with R-410A which causes your compressor and your system to operate more efficiently. R-22 oil will not flow through a 410A system and will most likely end up accumulating in your evaporator.
  • The new synthetic oil, POE, mentioned above absorbs moisture at a much faster rate than mineral oil. Because of this the time allowed for the compressor to be exposed to the atmosphere is much much shorter than what you may be used to for R-22. Best practice is to ensure everything is set and ready before pulling the plugs on the compressor.
  • Because R-22 is a single refrigerant and not a blend there was never any risk of a temperature glide. But, with R-410a since it is a blended refrigerant of R-32 and R-125 there will be a glide during refrigerant state changes. This is because the two refrigerants have different state change points. While I say this, the actual glide temperature difference for 410A is rather minimal at <0.5° Fahrenheit.  For more information on glide temp differences please click here to read an instructional document from Chemours.
  • Also, Since R-410A is a blended refrigerant it is best to evacuate the refrigerant as a liquid.  This ensures optimum and consistent performance. This is recommended by Chemours and other leading manufacturers.
  • Some techs have asked if they can retrofit an R-22 system over to an R-410A. The answer is yes, and no. It can be done but it is not cost effective or recommended. Instead Chemours has provided an alternative drop-in replacement to be used as a substitute to R-22. This refrigerant is known as MO99. Chemours has provided an instructional video on how to retrofit your existing unit to take MO99.
  • Lastly, it is VERY important that when replacing components on an R-410A unit rather they be reversing valves, expansion valves, driers, compressors, or whatever you have to make sure that the replacement you are installing is rated for R-410A usage. If they are not and they are exposed to the high pressure of R-410A you will have a failure, perhaps even a catastrophic failure.

Recommended 410A Tools

As we stated before the pressure rating on 410A is much higher then R-22. With this higher pressure from 410A comes a need for new tools. Let’s take a look:

  • Manifold Gauge Set – The high pressures encountered when working R-410A requires a manifold gauge set that has a low-side gauge that can read up to 500 PSIG and a high side gauge that can read up to 800 PSIG. This is significantly higher than a standard manifold set. There are many versions of gauges out there and by now I will imagine most of them meet 410A requirements.
    We recommend Yellow Jacket’s 49967 Manifold Gauge set. This is set is rated for both R-22 and R-410A along with a host of other refrigerants. Yellow Jacket’s official product flyer can be found by clicking here.
  • Hoses – Hoses used on 410A applications should be UL recognized and have a minimum of 800 PSI working pressure and a 4,000 PSI burst. This covers you by providing a five to one safety factor. I will refer to the recommended gauge set above as it comes with a set of four hoses as well. If you need to purchase additional hoses then again I would suggest the Yellow Jacket hose.
  • Flaring Tools – Depending on the unit you are working on you may find that you need to flare some of the tubes in order to get everything to fit correctly. While your existing flaring tool may work there is a chance of leaks when working with R-410A due to the pressure. There are flaring tools specifically designed for R-410A that will allow for ease of use and minimize chance of leaks.
    Our pick at RefrigerantHQ is Yellow Jacket’s 60278 410A Flaring Tool. You can find an instructional video by clicking here.
  • Refrigerant Leak detector – There are so many leak detectors out there on the market today it can be a little confusing. Most of them by now can detect R-410A along with other HFC refrigerants.
    To make things a little bit easier I put together a price point comparison table that can be found by clicking here. This will give you the option to pick a detector that will work for you as well as stay in your budget.
  • Recovery Cylinders – Recovery cylinders need to be rated to at least 400 DOT. A standard DOT 350 cylinder will not be able to safely handle the pressures of R-410A.
    We recommend that you purchase the Mastercool 62010 thirty pound recovery cylinder. This is a highly rated tank that can handle the high pressures of 410A refrigerant.
  • Recovery Machine – A recovery machine for 410A must be approved for Class V refrigerants including R-407C, R-404A, R-507, and R-410A per AHRI 740-98. The recovery machine should have the following features: over sized condenser, over sized fan, crankcase pressure regulator valve, and a high pressure cutout switch rated for at least 510 PSI. (Source from Yellowacket.com)
    We recommend that you purchase the Robinair RG3 Portable Recovery Machine. This is an overall great unit with tons of positive reviews and it can handle the pressures of 410A without a problem.


I know I may be a little behind the times here on getting this article out but I still wanted to publish and let anyone who still had some questions on their mind to get them answered.

Thanks for reading and as always if you see something that I missed or something that is incorrect please do not hesitate to contact me by clicking here.